Obesity is defined as having an abnormal increase of body fat which is also called adipose tissue mass. An obese person is 20 percent or more above desirable weight. In the last decade obesity has been on the rise in both women and men. Fat distribution can influence a person's risk of disease. Fat carried around the waist and in the abdominal area, characterized by the "apple shape", is associated with an increased risk for many medical problems such as heart disease, cancer, high blood pressure, and diabetes. Fat that is mostly distributed around the buttocks and thighs is associated with a lower risk of developing these diseases. As much as 50 to 75 percent of obesity has genetic influences. Just what those genetic influences are that affect body weight have not been identified. To achieve lasting weight loss, commitment must be given to making real changes in eating patterns. Individuals are who not committed will gain back their weight. During the holidays or when celebrating, many of us have overeaten. But some people have problems controlling their appetite and end up eating non-stop until eating is interrupted. Binge eating can be triggered by many things such as stress, depression, loneliness or anger. Food is used as a way of dealing with issues other than hunger. During a binge, 10,000 to 20,000 calories can be consumed throughout the day. Binges usually consist of foods like cookies, candy, chips, ice cream and many other high calorie foods. Binges are often done in secret. After a binge, many of the feelings that caused the binge, like stress, may have subsided only to be replaced with feelings of guilt and lack of self-control. The following guidelines have been developed that may help control binge eating:
- Eat only at established meal times.
- Avoid keeping foods around that may trigger bingeing.
- Avoid fad or very restrictive diets.
- Keep a food diary and log to assess what prompted the binge.
When the muscle's capacity to store fat is exceeded, excess fat is then stored outside the muscle, around body organs and under the skin. The fat that is now being added to the body results in the person becoming overfat and overweight. Studies show that a 20 percent increase in body weight increases the risk for heart disease, high blood pressure and diabetes. The risk of developing weight associated medical problems increases if the majority of body fat is located in the abdominal area. This risk decreases if body fat is primarily located in the hips, buttock and thigh region. Height and weight tables are generally used to determine how person's weight compares to a standard. However, weight in these tables is an overall measure of all components of the body. Individuals may differ in muscle, frame size and percentage of body fat. The waist to hip ratio of body composition assessment provides information on where the majority of body fat is located.
The medications most often used in the management of obesity are commonly known as "appetite suppressant" medications. Appetite suppressant medications promote weight loss by increasing metabolism and by decreasing appetite or increasing the feeling of being full. These medications work by increasing the serotonin and/or catecholamine - two brain chemicals that affect mood, appetite and metabolism. Over the short term, weight loss in obese individuals may reduce a number of health risks. Studies looking at the effects of appetite suppressant medication treatment on obesity-related health risks have found that some agents lower blood pressure, blood cholesterol, triglycerides (fats) and decrease insulin resistance (the body's inability to use blood sugar) over the short term. Long-term studies are currently being done to determine if weight loss from appetite suppressant medications can improve health. When considering long-term appetite suppressant medication treatment for obesity, you should consider the following areas of concern and potential risks. Currently, all prescription medications to treat obesity are controlled substances, meaning doctors need to follow certain restrictions when prescribing appetite suppressant medications. Although abuse and dependence are not common with non-amphetamine appetite suppressant medications, doctors should be cautious when they prescribe these medications for patients with a history of alcohol or other drug abuse. Most studies of appetite suppressant medications show that a patient's weight tends to level off after four to six months while still on medication treatment. While some patients and physicians may be concerned that this shows tolerance to the medications, the leveling off may mean that the medication has reached its limit of effectiveness. Based on the currently available studies, it is not clear if weight gain with continuing treatment is due to drug tolerance. However obesity, is more appropriately considered a chronic disease than a lifestyle choice. Other chronic diseases, such as diabetes, and high blood pressure, are managed by long-term drug treatment, even though these diseases also improve with changes in lifestyle, such as diet and exercise. Although this issue may concern physicians and patients, social views on obesity should not prevent patients from seeking medical treatment to prevent health risks that can cause serious illness and death.

Terms used on this pageFDA
- Food and Drug Administration: A government agency that oversees public safety in relation to drugs and medical devices. The FDA gives approval to pharmaceutical companies for commercial marketing of their products.
Fat blocker
- Drugs that block the absorption of fat or calories, and lose substantial weight.
Overweight
- Weighing more than is normal, necessary, or allowed, especially having more body weight than is considered normal or healthy for one's age or build.
Appetite
- An instinctive physical desire, especially one for food or drink. Decreased desire to eat is termed anorexia, while polyphagia (or "hyperphagia") is increased eating. Disregulation of appetite contributes to anorexia nervosa and cachexia, or oppositely, overeating.
Diabetes
- Any of several metabolic disorders marked by excessive discharge of urine and persistent thirst, especially one of the two types of diabetes mellitus.
Diet
- A regulated selection of foods, as for medical reasons or cosmetic weight loss.
- A solutions designed to reduce or suppress the appetite.
Fat
- Any of various soft, solid, or semisolid organic compounds constituting the esters of glycerol and fatty acids and their associated organic groups.
Obesity
- The condition of being obese; increased body weight caused by excessive accumulation of fat.
Stress
- A state of extreme difficulty, pressure, or strain.
- A physical and psychological response that results from being exposed to a demand or pressure.
Suppress
- To curtail or prohibit the activities of.
- To inhibit the expression of (an impulse, for example).
- To bring to an end forcibly as if by imposing a heavy weight.
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